We do have clients that work a full week and feel great. Just make sure that you are able to take a little time out for yourself. Depending on the type of work you are involved in, it is recommended that you rest as much as you can during your cleanse. There may be days where you feel tired or nauseated and it may be hard to concentrate on work. If your work involves physical activity, it is recommended that you take time off during your detox program.